For more details on the methods the USPTSF uses to determine net benefit, see the USPSTF Procedure Manual. See Table 2 for more information on the USPSTF recommendation rationale and assessment. The USPSTF recommendation for screening for colorectal cancer does not include serum tests, urine tests, or capsule endoscopy for colorectal cancer screening because of the limited available evidence on these tests and because other effective tests (ie, the recommended screening strategies) are available. See Table 1 for characteristics of recommended screening strategies. This assessment of net benefit applies to stool-based tests with high sensitivity, colonoscopy, computed tomography (CT) colonography, and flexible sigmoidoscopy. Adults who have never been screened for colorectal cancer are more likely to benefit. The USPSTF concludes with moderate certainty that screening for colorectal cancer in adults aged 76 to 85 years who have been previously screened has small net benefit. The USPSTF concludes with moderate certainty that screening for colorectal cancer in adults aged 45 to 49 years has moderate net benefit. The US Preventive Services Task Force (USPSTF) concludes with high certainty that screening for colorectal cancer in adults aged 50 to 75 years has substantial net benefit. Clinicians should understand the evidence but individualize decision making to the specific patient or situation. The USPSTF recognizes that clinical decisions involve more considerations than evidence alone. This includes more details on the rationale of the recommendation, including benefits and harms supporting evidence and recommendations of others. Visit the USPSTF website to read the full recommendation statement. The USPSTF has a recommendation statement on aspirin use to prevent cardiovascular disease and colorectal cancer, available at Where to read the full recommendation statement? What are other relevant USPSTF recommendations? Selectively screen adults aged 76 to 85 years for colorectal cancer.ĭiscuss together with patients the decision to screen, taking into consideration the patient’s overall health status (life expectancy, comorbid conditions), prior screening history, and preferences. Flexible sigmoidoscopy every 10 years + annual FIT.Computed tomography colonography every 5 years.High-sensitivity guaiac fecal occult blood test (HSgFOBT) or fecal immunochemical test (FIT) every year. Recommended screening strategies include: For example, the tests require different frequencies of screening, location of screening (home or office), methods of screening (stool-based or direct visualization), preprocedure bowel preparation, anesthesia or sedation during the test, and follow-up procedures for abnormal findings. Clinicians and patients may consider a variety of factors in deciding which test may be best for each person. Several recommended screening tests are available. Screen all adults aged 45 to 75 years for colorectal cancer. The USPSTF continues to recommend selectively screening adults aged 76 to 85 years for colorectal cancer. The USPSTF expanded the recommended ages for colorectal cancer screening to 45 to 75 years (previously, it was 50 to 75 years). Grade CĪdults 45 years and older who do not have signs or symptoms of colorectal cancer and who are at average risk for colorectal cancer (ie, no prior diagnosis of colorectal cancer, adenomatous polyps, or inflammatory bowel disease no personal diagnosis or family history of known genetic disorders that predispose them to a high lifetime risk of colorectal cancer ). Selectively screen adults aged 76 to 85 years for colorectal cancer, considering the patient’s overall health, prior screening history, and patient’s preferences. Screen adults aged 45 to 49 years for colorectal cancer. Screen all adults aged 50 to 75 years for colorectal cancer.
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